Custom Enzymes and Inhibitors
Selleck Chemical LLC Y-27632 2HCl 2mg 129830-38-2
Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC HY-110155A 5mg Medchemexpress, (Rac)-LM11A-31 (dihydrochloride) CAS:1214672-15-7 Purity:>98%
Medchemexpress, HY-110155A 5mg (Rac)-LM11A-31 (diHCl) CAS:1214672-15-7 (Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-110155A 10mg Medchemexpress, (Rac)-LM11A-31 (dihydrochloride) CAS:1214672-15-7 Purity:>98%
Medchemexpress, HY-110155A 10mg (Rac)-LM11A-31 (diHCl) CAS:1214672-15-7 (Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Sid 26681509 quarterhydrate | 00-00-0 | 98.0% | 544.16 g/mol | C27H33N5O5S.1/4H2O | 5 MG
Potent, reversible, competitive inhibitor of human cathepsin L (IC50 = 56 nM) with reported antiparasitic activity in vitro. Supplied as a white to off-white solid with high reported purity, the compound is provided in milligram quantities and as a ready-to-use DMSO solution for biochemical and antiparasitic research.
- Selective cathepsin L inhibition (IC50 = 56 nM).
- Inhibits Plasmodium falciparum and Leishmania major in vitro.
- High reported purity (98.02%).
- White to off-white solid; also available as a 10 mM solution in DMSO.
- Available in small milligram package sizes suitable for biochemical assays.
Selleck Chemical LLC Emtricitabine 50mg 143491-57-0
Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Nilotinib (AMN-107) 25mg 641571-10-0
Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC SB525334 5mg 356559-20-1
SB525334 is a potent and selective inhibitor of TGF? receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC SU11274 5mg 658084-23-2 PKI-SU11274
SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFR?, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Emtricitabine 10mg 143491-57-0
Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Palbociclib (PD0332991) Isethionate 10mg 827022-33-3
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Trichostatin A, (1mg), CAS Number: 58880-19-6
HDAC inhibitor. Alternative Name: R-(E E)-7-4-(Dimethylamino)phenyl-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide. Formula: C17H22N2O3. MW: 302.4. CAS Number: 58880-19-6. Purity: ≥98% (HPLC). Appearance: Off-white to beige solid. Solubility: Soluble in DMSO, dimethyl formamide, acetonitrile, methanol or 100% ethanol. Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. Long Term Storage: -20°C
Enzo Life Sciences SUMO-2 aldehyde (25 µg)
Inhibitor of deSUMOylating enzymes (SENPs). SUMO-2 aldehyde is a highly specific inhibitor of SENP enzymes and has utility in the stabilisation of SUMO-protein conjugates in vitro, enhancing their accumulation in cell lysates and tissue extracts. In addition, co-crystallisation of yeast SUMO (Smt3) aldehyde with the yeast deSUMOylating enzyme Ulp1 has been used to probe the enzyme: substrate interactions, so human SUMO-aldehydes may therefore be of similar utility, and SUMO-2 aldehyde may be used in conjunction with SUMO-1 aldehyde to probe the SUMO paralogue preference of SENP enzymes. Inhibitor of deSUMOylating enzymes (SENPs). SUMO-2 aldehyde is a highly specific inhibitor of SENP enzymes and has utility in the stabilisation of SUMO-protein conjugates in vitro. Alternative name: Sentrin 2 aldehyde. Concentration: 1mg/ml. Purity: ≥95% (HPLC). Formulation: Liquid. In 0.15M HCl. Source: Produced in E. coli cells. Derivatised chemically, in vitro.
